The SmartState Center for Translational Cancer Therapeutics at the College of Pharmacy was established in 2011 under the direction of Igor Roninson, Ph.D., through a state-funded endowed chair program.
Principal Research Interests
Our principal research interests include:
- developing personalized cancer therapy based on target and drug discovery through functional genomics and chemical genomics (Roninson, Shtutman)
- chemical genomics of tumor microenvironment (Roninson, Kiaris, Broude)
- mechanisms and pharmacological modulation of a damage-inducible signal transduction pathway implicated in cancer
- maintenance of chromosome stability by homologous recombination (HR) DNA repair mechanisms and cancer progression (Wyatt, Pittman)
- developing combinatorial approaches of newly discovered drugs with existing therapies for breast and prostate cancer (Broude, Roninson, Chen)
- Igor Roninson, Ph.D., Smartstate Endowed Chair
- Eugenia Broude, Ph.D.
- Michael Shtutman, Ph.D.
- Hippokratis Kiaris, Ph.D.
- Mythreye Karthikeyan, MSc., Ph.D.