Light-matter interactions are ubiquitous and remain in the forefront of research in physics, chemistry, biology, and engineering. Understanding these processes microscopically plays an important role in a wide variety of applications, from optically manipulating material properties on the nanometer level to obtaining information on distant galaxies on a cosmological scale. The current curriculum in the Department of Physics and Astronomy covers the basic understanding of light-matter interactions. However, it does not provide a complete explanation of all optical phenomena observed nor the skills for students to theoretically model optical measurements. This new course will concentrate on addressing this knowledge gap and provide a deeper and fuller understanding of the topic from a microscopic and quantum-mechanical point of view. It should also have a cross-disciplinary appeal to multiple units in the University, such as Chemistry and Electrical Engineering.