Neural Mechanisms of Speech Production and Motor Control
In our lab, we utilize the EEG recording technique to investigate neural mechanisms
of speech production and motor control. The goal of this research is to understand
how different areas of the human brain are involved when speakers produce speech sounds
and control different parameters of their voice.
Another aspect of our research is related to measuring brain activity using functional
magnetic resonance imaging (fMRI). The fMRI recordings allow us to take a closer look
at the brain structures that are activated during speech production and motor control.
These data are useful to examine the sensory-motor networks of the human brain that
facilitate human communication during speech.
Speech Disorder in Post-Stroke Aphasia
The goal of this research is to understand how stroke-induced damages to different
brain areas can result in speech and language disorders in patients with aphasia.
We utilize a combination of novel behavioral testing and neuroimaging technologies
to delineate neural networks involved in speech production and motor control and their
impairment in aphasia. These methodologies include Voxel-Base Lesion-Symptom-Mapping
(VLSM) and Tractography-Based Connectome-Symptom-Mapping (CSM) analyses to study how
damages to the gray matter and white matter tracts is related to pathological alteration
of speech and language function in aphasia. The outcome of this research can promote
the scientific and clinical knowledge for targeted treatment of speech and language
disorders in patients with post-stroke aphasia.
Speech Disorder in Parkinson’s Disease
About 90% of patients with Parkinson’s disease develop speech disorders at some stages
in their life. We currently have a number of ongoing research studies to better understand
the neurological bases of speech motor disorders in Parkinson’s disease. The goal
of these projects is to provide new knowledge that can contribute to the development
of novel clinical diagnosis and treatment methods for speech disorders in patients
with Parkinson’s disease and other neurological deficits.
Speech Disorder Treatment using High-Definition Neurostimulation Technology (HD-tDCS)
Our lab is currently conducting research on a funded project to investigate the effect
of non-invasive neuro-stimulation on the mechanisms of speech production and motor
control. The long-term goal of this project is to promote our knowledge about the
application of neurostimulation as a clinical method for the treatment of speech motor
disorder in patients with neurological diseases.
Challenge the conventional. Create the exceptional. No Limits.