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Office of Research and Grant Development

Program Details

Integrated Biological and Computational Low Dose Radiation Research DE-FOA-0003281

Sponsor: DOE
Internal Deadline: 12/22/2023
Institutional Submission Limit: 1
Sponsor Deadline: 02/06/2024
Program Website

DOE SC program in Biological and Environmental Research (BER) hereby announces its interest in development of integrated biological and computational research to gain a mechanistic understanding of the effects of low dose radiation exposure on cellular functions. The long-term goal is to build on the understanding of radiation effects on cellular function and establish comprehensive datasets amenable to incorporation into increasingly capable AI/ML models to identify both transient and persistent changes in cellular metabolism that may be linked to adverse health outcomes.

This funding opportunity calls for biological research applications conducted with well-defined and/or known exposures to low energy transfer (LET) radiation sources (high energy electrons, protons, x- and gamma rays) across a range of low dose exposures (<100mGy encompassing 10mGy) and dose rate ranges encompassing 5mGy/hr within four topics (see call:

  • Submission Deadline for Pre-Applications: February 6, 2024 at 5:00 PM ET (A Pre-Application is required. Pre-Applications must be submitted by an authorized institutional representative.)

  • Pre-Application Response Date:February 20, 2024 at 5:00 PM ET

  • Submission Deadline for Applications:April 2, 2024 at 11:59 PM ET


Submission Process

Limited submissions MUST be coordinated with the Office of the Vice President for Research.

If interested in applying for this opportunity, email a two-page project abstract, include at top the project title, PI, and list of key collaborators, as well as a 2-3 page CV/biosketch for the PI (SCiENcv preferred) by 5pm on the INTERNAL DEADLINE above to Julie Morris at

Office of Research and Grant Development

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