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College of Pharmacy

COBRE Publications (2017-18)

Through a variety of publications, the COBRE Center for Targeted Therapeutics offers news and information on the latest in targeted cancer therapeutics research. We encourage you to explore information presented by our experts in the form of magazine, journal, and newsletter articles.

Publishers Publication Title Year Keywords
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Lunev S, Semmelink MF, Xian JL, Ma KY, Leenders AJ, Dömling AS, Shtutman M, Groves MR. 

Crystal structure of truncated human coatomer protein complex subunit ζ1 (Copζ1). Acta crystallographica. Section F, Structural biology communications. 

2017 January 1; 73 (Pt 1):1-8.  
Shtutman M, Chang BD, Schools GP, Broude EV.  Cellular Model of p21-Induced Senescence. Methods in molecular biology (Clifton, N.J.).  2017; 1534: 31-39.  
McDermott MS, Chumanevich AA, Lim CU, Liang J, Chen M, Altilia S, Oliver D, Rae JM, Shtutman M, Kiaris H, Győrffy B, Roninson IB, Broude EV. Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer. Oncotarget.  2017 February 21; 8(8):12558-12575.   
Pan CC, Shah N, Kumar S, Wheeler SE, Cinti J, Hoyt DG, Beattie CE, An M, Mythreye K, Rakotondraibe LH, Lee NY. 

Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy. Oncotarget. 2017 February 21; 8 (8):12675-12685.

2017 February 21; 8 (8):12675-12685.  
Oliver D, Ji H, Liu P, Gasparian A, Gardiner E, Lee S, Zenteno A, Perinskaya LO, Chen M, Buckhaults P, Broude E, Wyatt MD, Valafar H, Peña E, Shtutman M.

Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen. Scientific reports. 2017 February 22; 7: 43023.

2017 February 22; 7: 43023.  

Chukwurah E, Handy I, Patel RC. 

ADAR1 and PACT contribute to efficient translation of transcripts containing HIV-1 trans-activating response (TAR) element. The Biochemical journal. 2017 March 23; 474 (7):1241-1257. 2017 March 23; 474 (7):1241-1257.  

Varadaraj A, Jenkins LM, Singh P, Chanda A, Snider J, Lee NY, Amsalem-Zafran AR, Ehrlich M, Henis YI, Mythreye K. 

TGF-β triggers rapid fibrillogenesis via a novel TβRIIdependent fibronectin-trafficking mechanism. Molecular biology of the cell.  2017 May 1; 28(9):1195-1207.  

Chen M, Liang J, Ji H, Yang Z, Altilia S, Hu B, Schronce A, McDermott MSJ, Schools GP, Lim CU, Oliver D, Shtutman MS, Lu T, Stark GR, Porter DC, Broude EV, Roninson IB. 

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB. Proceedings of the National Academy of Sciences of the United States of America. 2017 September 19;114(38):10208-10213 2017 September 19;114(38):10208-10213  
Chapman CD, Schiöth HB, Grillo CA, Benedict C.  Intranasal insulin in Alzheimer's disease: Food for thought. Neuropharmacology. 2017 November 24. 2017 November 24.  

Choi RH, McConahay A, Jeong HW, McClellan JL, Hardee JP, Carson JA, Hirshman MF, Goodyear LJ, Koh HJ. 

Tribbles 3 regulates protein turnover in mouse skeletal muscle. Biochemical and biophysical research communications.  2017 November 25; 493(3):1236-1242.  
Manuel AM, Walla MD, Faccenda A, Martin SL, Tanis RM, Piroli GG, Adam J, Kantor B, Mutus B, Townsend DM, Frizzell N.  Succination of Protein Disulfide Isomerase Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes. Antioxidants & redox signaling.  2017 December 1; 27(16):1281-1296.  

Jenkins LM, Horst B, Lancaster CL, Mythreye K. 

Dually modified transmembrane proteoglycans in development and disease. Cytokine & growth factor reviews.  2017 December 22.  

Chukwurah E, Patel RC.

Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival. Scientific reports. 2018 January 18; 8(1):1020.  

Alam A, Küng R, Kowal J, McLeod RA, Tremp N, Broude EV, Roninson IB, Stahlberg H, Locher KP. 

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proc Natl Acad Sci U S A. 2018 Feb 27; 115(9):E1973-E1982. Epub 2018 Feb 13.