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College of Pharmacy

CTT News Room

Charlie Bennett

When antibiotics turn toxicCommonly prescribed drugs called fluoroquinolones cause rare, disabling side effects. Researchers are struggling to work out why.

Jeff Twiss

Dr. Jeff Twiss' study published in Science This study identifies a major new mechanism regulating neuronal injury, offering a potential therapeutic strategy for treating such injury.

Eugenia Broude (target PI)

NIH/NCI grant No. 1R43CA221485-01 “CDK8/19 inhibitor for the treatment of HER2+ breast cancer”. 07/01/2017 – 06/30/2018. Total costs: $280,367

Claudia Grillo (pilot project PI)

National Science Foundation (NSF) grant No. 1656626 “Identifying a new circuit that controls feeding behavior: leptin and serotonin interactions”. 05/15/2016 – 04/30/2020. Total costs: $900,000.

Dr. Jing Fang (target PI)

 NIH/NCI grant No. 1R01CA218076-01 “Targeting the p62 signalosome in leukemia”. Budget period: 08/01/2017 – 07/31/2022. Total costs: $1,831,250.

Pavel Ortinski (pilot project PI)

NIH/NIDA grant No. 1R01DA041513. “Neural microcircuit selection by astrocyte signaling following cocaine exposure”, 02/01/2017 – 11/30/2022. Total costs: $1,501,875.

Michael Shtutman (former target PI)

NIH/NIDA grant No. 1R03DA043428-01A1 “Functional identification of new mechanisms of neurotoxicity induced by HIV and drugs of abuse”, 02/01/2017 - 01/31/2019. Total costs: $293,000. (Co-PI Dr. Jun Zhu)

Norma Frizzell (former target PI)  

 NIH/NIDDK grant No. 1R56 DK105087-01 “Protein Succination: a Mechanistic Mediator of Adipocyte Dysfunction in Diabetes” (08/01/2015 - 07/31/2017). Total costs: $267,000.NIH/NINDS grant No. 1R01NS092938 “Protein Succination as a Mediator of Neuropathology in Mitochondrial Disease” (09/01/2015 - 05/31/2019). Total costs: $862,676.

Rekha Patel (former pilot project PI)

 DoD CDMRP Discovery Award PR172093 “Dysregulation of the PACT-mediated crosstalk between protein kinases PKR and PERK contributes to dystonia 16 (DYT16)” 05/01/2018-10/31/2019. Total costs: $292712. USC internal funding ASPIRE-II. “Influence of mitochondrial ND5 sequence on average lifespan of Daphnia pulex”. 07/01/2016-09/30/2018 Total costs: $100,000. USC internal funding ASPIRE-II “Chronic social stress and accelerated aging among South Carolina women: Investigating the social, behavioral, and biological influences on aging processes”. 07/01/2017-09/30/2018 (co-PI, Moore) Total costs: $100,000

George Petkov (former pilot project PI)  

NIH/NIDDK grant No. 1R01DK106964-01. “Role of TRP channels in human detrusor function and disfunction”. 08/07/2015 – 04/30/2020. Total costs: 1,664,050.

Ho-Jin Koh (former pilot project PI)

NIH/NIAMS grant No. 1R03 AR066825-01A1 “TRB3: A Novel Mediator for Denervation-induced Muscle Atrophy”, 06/01/2015 – 03/31/2018. Total costs: $219,750.  

Peisheng Xu (former target PI)

NIH/NIGMS Grant No. 5P30GM103336-02, a pilot grant. “A Nano-Cocktail Delivery System for Colon Cancer Therapy”, 08/01/2014 - 07/31/2015. Total costs: $58,000. NIH/NCI grant No. 1R15CA188847-01A1 “Nano-cocktail Overcomes Multidrug-Resistance for Ovarian Cancer Therapy” 07/01/2015 - 06/30/2018. Total costs: $366,250. NIH/NIAG grant No. 1R01AG054839 “Brain targeted nanoparticle for Alzheimer's disease therapy”. Budget period: 03/01/2017 – 02/28/2022. Total costs $1,501,625 (Co-I, Kelly MP)

Michy Kelly (former target PI)

NIH/NIMH Grant No. 5R01MH101130-02. “Compartmentalization of Cyclic Nucleotide Signaling in the Ventral Hippocampus” 07/08/2014 – 04/30/2019, Total cost: $1,668,750. University of South Carolina ASPIRE III Grant. “Acquisition of Logos X-ClarityTM Tissue Clearing System and Confocal Microscopy Objective for the USC Instrumentation Resource Facility” ($64,390; PI Price B; Co-I Kelly MP). 2015 - 2017 Brain and Behavior Research Foundation NARSAD Young Investigator Grant, “Dissecting the molecular and anatomical pathways of recent versus remote long-term memory” ($65,000 over 2 years; P.I., MP Kelly)