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Office of Research and Grant Development

Program Details

Diagnostic Centers of Excellence for the Undiagnosed Diseases Network (U01 – Clinical Trial Not Allowed) PAR-23-289

Sponsor: NIH
Internal Deadline: 09/08/2023
Institutional Submission Limit: 1
Sponsor Deadline: 11/03/2023
Program Website

The purpose of this Notice of Funding Opportunity is to solicit applications for clinical sites that will provide expert diagnostic services for undiagnosed diseases across the nation. The clinical sites known as Diagnostic Centers of Excellence (DCoEs) will partner with the Undiagnosed Diseases Network (UDN) to sustain some of the key research activities currently performed by the Phase II UDN Clinical sites (see:RFA-RM-17-019) and facilitate its transition to a larger network that serves undiagnosed patient populations including minority health and other populations defined by the NIH to experience health disparities. The DCoEs will establish collaborations and efficient processes with the Data Management and Coordinating Center (DMCC; see: RFA-NS-22-051); enroll and evaluate new participants; and foster scientific discovery.

This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn.

Applicants are strongly encouraged to read the FOA instructions carefully and view the available PEDP guidance material.

Submission Process

Limited submissions MUST be coordinated with the Office of the Vice President for Research.

If interested in applying for this opportunity, email a two-page project abstract, include at top the project title, PI, and list of key collaborators, as well as a 2-3 page CV/biosketch for the PI (SCiENcv preferred) by the INTERNAL DEADLINE above to Julie Morris at

Office of Research and Grant Development

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