Skip to Content

Office of Research and Grant Development

Program Details

NIH: Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2015 and 2016 (P50) PAR-14-353

This Funding Opportunity Announcement (FOA) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPOREs). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer (or a related group of cancers). For the purpose of this funding announcement, cancers derived from the same organ system (i.e., group of organs that perform common function) are considered related. Examples of such organ systems include gastro-intestinal, endocrine, circulatory, and other biological systems. Other programmatically appropriate groups of cancers may include those centered around a common biological mechanism critical for promoting tumorigenesis and/or cancer progression in organ sites that belong to different organ systems. For example, a SPORE may focus on cancers caused by the same infectious agent, or sustained and promoted by dysregulation of a common signaling pathway. SPOREs are expected not only to conduct a wide spectrum of research activities, but also to contribute significantly to the development of specialized shared resources core facilities, improved research model systems, and collaborative research projects with other institutions. The research supported through this program must be translational in nature and must always be focused upon knowledge of human biology stemming from research using cellular, molecular, structural, biochemical, and/or genetic experimental approaches with the goal of a translational human endpoint within the project period of the grant. In addition, SPOREs must include both a Developmental Research Program for pilot studies and a Career Enhancement Program to foster careers in translational research related to the focus of the SPORE.

USC may only submit one application in response to this program announcement. Your application submission MUST be coordinated with the Office of the Vice President for Research. Please send a two page abstract via email to Richard White ( by March 20, 2015. In addition to the 2-page abstract, you should also submit a biosketch for the PI.

NSF indicates that a letter of intent is due on April 17, 2015 and a full proposal is due by May 19, 2015. For more information:

Office of Research and Grant Development

    Challenge the conventional. Create the exceptional. No Limits.