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Office of Research and Grant Development

Program Details

NIAMS: Validation of Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium (U19)RFA-AR-15-014

The purpose of this FOA is to solicit applications for the Validation of Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium. The NIAMS, on behalf of the National Institutes of Health, intends to capitalize on recent advances in the science of Patient Reported Outcomes (PROs) to measure the patient experience in clinical care and research in children with a variety of chronic diseases and conditions (e.g., asthma, juvenile arthritis, cystic fibrosis, diabetes, obesity and overweight, chronic kidney disease, inflammatory bowel disease, sickle cell disease, malnutrition, developmental disabilities including attention deficit/hyperactivity disorder and autism spectrum disorder, cerebral palsy and mental illnesses) using the Patient-Reported Outcomes Measurement Information System (PROMIS) tools and approaches coupled with detailed clinical phenotyping and/or biospecimen collection in well-characterized human cohorts. The Patient Reported Outcomes Measurement Information System (PROMIS) is a system of highly reliable, precise measures of patient–reported health status for physical, mental, and social well–being. PROMIS tools measure what patients are able to do and how they feel by asking questions. PROMIS’ measures can be used as primary or secondary endpoints in clinical studies of the effectiveness of treatment.

USC may only submit one application in response to this program announcement. Your application submission MUST be coordinated with the Office of the Vice President for Research. Please send a two page abstract via email to Richard White ( by March 31, 2015. In addition to the 2-page abstract, you should also submit a biosketch for the PI. Prior applicants should also attach a copy of their most recent reviews with their 2 page abstract.

NIAMS indicates that a letter of intent is due May 2, 2015 and a full proposal is due by June 2, 2015. For more information:

Office of Research and Grant Development

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