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Carolina Autism and Neurodevelopment Research Center

Expertise

The Carolina Autism and Neurodevelopment Research Center (CAN) brings together researchers across the University of South Carolina who study autism and other neurodevelopmental disorders (NDDs). Our faculty represent a wide range of disciplines and methodological approaches, allowing CAN to support innovative, collaborative research that improves understanding, diagnosis and support for individuals and families.

CAN investigators contribute expertise in clinical research, neuroscience, education, public health and community engagement. By combining these perspectives, the center advances discoveries that translate into real-world impact.

Neurodevelopmental Conditions

CAN researchers study a broad range of neurodevelopmental conditions, including:

  • Autism spectrum disorder (ASD)
  • Attention-deficit/hyperactivity disorder (ADHD)
  • Intellectual and developmental disabilities
  • Learning differences and language disorders
  • Anxiety disorders
  • Intersections between co-occurring mental health conditions (e.g., autism + anxiety)

Clinical Research Approaches

Our faculty use diverse research methods to understand neurodevelopment and improve outcomes, including:

  • Behavioral and cognitive assessment
  • Neuroimaging and neuroscience methods (e.g., fMRI, EEG)
  • Physiological methods (e.g., eye tracking, heart rate) 
  • Clinical and intervention research
  • Educational and school-based research
  • Population and public health studies
  • Community-engaged and participatory research

Basic Neuroscience Research Approaches

Across CAN, our faculty are leading advances in neuroscience methods and tools used to understand neurodevelopment, neurodegeneration, and pharmacological interventions, including:

  • Molecular and cellular mechanisms 
  • Animal models and in vivo systems
  • Biochemistry and metabolic approaches
  • Genetic and developmental tools
  • Proteomics and protein chemistry
  • Chemical biology & small molecule therapeutics and pharmacology
  • Translational preclinical therapeutic strategies 
  • Computational and chemionformatic tools

Lifespan Perspective

CAN research spans the lifespan, examining development and support needs from early childhood through adulthood. Areas of focus include:

  • Early identification and diagnosis
  • School and educational supports
  • Social communication and development
  • Mental health and well-being
  • Family and caregiver experiences
  • Transition to adulthood and community participation

Collaboration and Impact

CAN supports interdisciplinary collaboration across the University of South Carolina and with partners across South Carolina and beyond. Through shared expertise, training, and community partnerships, the center advances research that improves the lives of individuals with autism and other neurodevelopmental conditions.


Challenge the conventional. Create the exceptional. No Limits.

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