Center for Clinical and Translational Research

2026 News

The Combination of PD-L1 and CTLA-4 Nano-ERASERs for TNBC Therapy

This project aims to develop a novel nanoparticle-based immunotherapy approach for treating triple-negative breast cancer (TNBC), one of the most aggressive and difficult-to-treat forms of breast cancer.

Prisma Health-USC Tumor Repository and Xenograft Pilot Project

This project is establishing the workflow for growing and testing pediatric patient-derived tumor organoids and will use innovative drug-screening approaches to test approved oncology drugs and abbapolins in pediatric cancer models.

Train Your Brain SC: An Exercise Intervention for People with Cognitive Impairments

This project aims to develop and evaluate a structured exercise and coaching program for individuals with mild to moderate cognitive impairments in South Carolina. By expanding access to structured exercise interventions, this study addresses a critical gap in care for individuals experiencing cognitive decline.

Investigating Factors Underlying the Progression of Diabetes Complications

This project is investigating if the incidence of specific protein modifications is associated with the progression of diabetes-related complications. Diabetes affects a significant portion of South Carolina's population and is a leading cause of blindness, kidney failure, and amputations. The study focuses on the measurement of stable protein adducts that are representative of maladaptive mitochondrial metabolism that may drive inflammation during diabetes.

Prisma Health Education and Research Institute Showcase

ClinTrUSC Team Members Prisma Health Research Showcase

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