Education

M.Eng.  Computer Science, University of South Carolina, 2016
MBA  Central South University, Changsha, China, 2008

Background

Hao "Emily" Ji's specific interests cover a broad range of technology including molecular cloning, cell culture, immunology-based protein analysis, lentivirus production, preparation of high-throughput libraries, next-generation sequencing, processing NGS data and basic bioinformatics / statistical analysis. 

Ji serves as the Facility Manager for the COBRE Center for Targeted Therapeutics’ Functional Genomics Core, which provides the University of South Carolina and outside partners with capacity to conduct genomics, transcriptomics, epigenomics and functional genomics research projects. It also provides common molecular biology services including nucleic acid purification and quantification, sequencing, Real time PCR analysis, plasmid construction and lentivirus production.

Publications

Weige CC, Birtwistle MR, Mallick H, Yi N, Berrong Z, Cloessner E, Duff K, Tidwell J, Clendenning M, Wilkerson B, Farrell C, Bunz F, Ji H, Shtutman M, Creek KE, Banister CE, Buckhaults PJ.  Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans. Mol Cancer Res. 2014: 12(7):1029-41.  PMID: 24743655

Gasparian A, Daneshian L, Ji H, Jabbari E, Shtutman M. Purification of high-quality RNA from synthetic polyethylene glycol-based hydrogels. Anal Biochem. 2015: 484:1-3. PMID: 25963891

Levina E, Biag M, Ji H, Chen M, Oliver D, Ohouo P, Lim CU, Carmack S, Ding Y, Roninson I, Buttyan R, Shtutman M. Identification of Novel Genes that Regulate Androgen Receptor Signaling and Growth of Androgen-Deprived Prostate Cancer Cells. OncoTarget 2015: 6(15):13088-104. PMID: 26036626

Gomez AM, Altomare D, Sun WL, Midde NM, Ji H, Shtutman M, Turner JR, Creek KE, Zhu J. Prefrontal microRNA-221 Mediates Environmental Enrichment-Induced Increase of Locomotor Sensitivity to Nicotine. Int J Neuropsychopharmacol. 2015 19(1). PMID: 26232787

Hegde S, Ji H, Oliver D, Patel NS, Poupore N, Shtutman M, Kelly MP. PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain. Neuroscience 2016, 335:151-69. PMID: 27544407

Oliver D, Ji H, Liu P, Gasparian A, Gardiner E, Lee S, Zenteno A, Perynskaya L, Chen M, Buckhaults P, Broude E, Waytt MD, Valafar H, Pena E, Shtutman M. Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen. Scientific Reports 2017, 7:43023. PMID: 28223711

Chen M, Liang J, Ji H, Yang Z, Altilia S, Hu B, Schronce A, McDermott MS, Schools GP, Lim CU, Oliver D, Shtutman M, Lu T, Stark GR, Porter DC, Broude EV, Roninson IB. CDK8/19: druggable co-regulators of NFκB-induced transcription. Proc. Natl. Acad. Sci. USA, 2017 114(38):10208-10213. PMID: 28855340

Lee SJ, Oses-Prieto JA, Kawaguchi R, Sahoo PK, Kar AN, Rozenbaum M, Oliver D, Chand S, Ji H, Shtutman M, Miller-Randolph S, Taylor RJ, Fainzilber M, Coppola G, Burlingame AL, Twiss JL. hnRNPs Interacting with mRNA Localization Motifs Define Axonal RNA Regulons. Mol Cell Proteomics. 2018 Nov;17(11):2091-2106. PMID: 30038033

Li J, Ji H, Porter DC, Broude EV, Roninson IB, Chen M. Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay. Cells. 2019 Oct 6;8(10):1208. PMID: 31590445

Aksenova M, Sybrandt J, Cui B, Sikirzhytski V, Ji H, Odhiambo D, Lucius MD, Turner JR, Broude E, Peña E, Lizarraga S, Zhu J, Safro I, Wyatt MD, Shtutman M. Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation. J Neuroimmune Pharmacol. 2020 Jun;15(2):209-223. PMID: 31802418

Chavez B, Farmaki E, Zhang Y, Altomare D, Ji H, Soltnamohammadi E, Shtutman M, Chatzistamou I, Kiaris H. A strategy for the identification of paracrine regulators of cancer cell migration. Clin Exp Pharmacol Physiol. 2020 Oct;47(10):1758-1763. PMID: 32585033

Lucius MD, Ji H, Altomare D, Doran R, Torkian B, Havighorst A, Kaza V, Zhang Y, Gasparian AV, Magagnoli J, Shankar V, Shtutman M, Kiaris H. Genomic variation in captive deer mouse (Peromyscus maniculatus) populations. BMC Genomics. 2021 Sep 14;22(1):662. PMID: 34521341

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