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College of Pharmacy

Faculty and Staff

S. Scott Sutton, Pharm.D.

Title: Department Chair, Clinical Pharmacy and Outcomes Sciences
Professor
Department: Clinical Pharmacy and Outcomes Sciences (CPOS)
College of Pharmacy
Email: sutton@cop.sc.edu
Phone: 803-777-0477
Office: College of Pharmacy
715 Sumter Street - CLS 311D
Columbia, SC 29208
Scott Sutton portrait

Administrative Responsibilities

The department chair for Clinical Pharmacy and Outcomes Sciences serves as a departmental leader, reporting directly to the dean while overseeing operations and faculty matters related to teaching, research, and service. As an academic leader, the chair guides department planning, establishes workload evaluation processes, and represents the department within the university.

Key operational responsibilities include faculty appointments and reviews, staff performance management, budget oversight, and space allocation. The chair approves research projects, ensures compliance with university policies, and assigns departmental duties. The chair also maintains professional relationships with external partners and manages contractual agreements in collaboration with administration. The chair plays a crucial role in addressing student academic concerns and implementing university policies while serving as an advisor and mentor to department faculty.


See: Our Administration

 
Education

Pharm.D.  University of South Carolina, 1998
B.S. Pharmacy  University of South Carolina, 1997

Background

S. Scott Sutton, Pharm.D., is a professor and chair of the Department of Clinical Pharmacy and Outcomes Sciences at the University of South Carolina College of Pharmacy. As department chair, Dr. Sutton provides strategic leadership for a multidisciplinary faculty and staff, fostering excellence in teaching, research, and service while advancing the department’s national visibility in pharmacy education and outcomes science.

Dr. Sutton is a nationally recognized pharmacy outcomes researcher whose work focuses on pharmacoepidemiology, real-world evidence, and data science–driven evaluations of medication safety, effectiveness, and comparative outcomes. His research program emphasizes team science and large-scale data integration, leveraging administrative claims data, electronic health records, and advanced analytic methods to address clinically meaningful questions aligned with federal and foundation funding priorities. He has secured funded grants spanning cancer, HIV, cardiovascular disease, infectious diseases, drug repurposing, and outcomes research, and regularly collaborates with clinicians, data scientists, and translational investigators.

In addition to his research leadership, Dr. Sutton is a dedicated and award-winning educator. He teaches across the professional pharmacy curriculum and is the lead instructor for a nationally recognized pharmacy review course that supports pharmacy education and licensure preparation. This course runs in parallel with his textbook, lecture video series, and question bank published by McGraw Hill and available on the Access Pharmacy platform, resources that are widely used by pharmacy students and educators nationwide.

Dr. Sutton has received multiple teaching and research awards from the University of South Carolina and previously served as a sports medicine pharmacist for the Department of Athletics. Outside of academia, he is an avid golfer and Gamecock fan, and most enjoys spending time with his wife and son.

Research Interests

  • Pharmacoepidemiology
  • Drug discovery / drug repurposing
  • Medication effectiveness and safety
  • Infectious diseases
  • Inflammation

Awards & Honors

  • Researcher of the Year, USC College of Pharmacy
  • Excellence in Scholarship, Department of Clinical Pharmacy and Outcomes Sciences, USC College of Pharmacy
  • Clinical Practice Teaching Award, University of South Carolina
  • Excellence in Service, USC College of Pharmacy
  • Professor of the Year, USC College of Pharmacy

Naplex Review Guide 5th edition. New York, McGraw Hill. 2025. McGraw Hill Education.

AI-based mining of biomedical literature. Applications for drug repurposing for the treatment of dementia. Artif Intell Med. 2025 Oct;168:103218. doi: 10.1016/j.artmed.2025.103218.

Clinical and Healthcare Resource Use Outcomes Associated with Resistance to Antiretroviral Therapy Among Veterans with Human Immunodeficiency Virus. Open Forum Infect Dis. 2025 Jun 9;12(7):ofaf340. doi: 10.1093/ofid/ofaf340. PMID: 40635909.

Association of nuceloside reverse transcriptase inhibitor use with reduced risk of Alzheimer’s disease risk. Alzheimers Dement 2025;21e70180.

NLRP3 activation with bisphosphonate use and th risk of incident age-related macualr degeneration. Invest Ophthalmol Vis Sci. 2025 Mar 3;66(3):32. doi: 10.1167/iovs.66.3.32.

Schizophrenia, off-label antipsychotics, and dementia risk in people with HIV. J Acquir Immune Defic Syndr. 2025 Feb 1;98(2):133-142. doi: 10.1097/QAI.0000000000003545.

Targeting the cholinergic anti-inflammatory pathway for type 2 diabetes prevention: a retrospective cohort study. Diabetes, Diabetes Obes Metab. 2025 Feb;27(2):675-682. doi: 10.1111/dom.16060.

Facilitating drug repurposing – Using databases for drug discovery in AMD. JAMA Ophthalmol. 2024 Aug 1;142(8):759-760. doi: 10.1001/jamaophthalmol.2024.2516.

Alzheimer disease treatment with acetylcholinesterase inhibitors and incident age-related macular degeneration. JAMA Opthalmol 2024;142(2):10-8114. doi: 10.1001/jamaophthalmol.2023.6014.

Anti-HIV drugs reduce risk of prediabetes and progression to type 2 diabetes in HIV-infected patients. MedComm-Future Medicine 2023; DOI: 10.1002/mef2.37.

Real-world clinical outcomes among US Veterans with oral factor Xa inhibitor-related major bleeding treated with andexanet alfa or 4-factor prothrombin complex concentrate. J Thromb Thrombolysis 2023;56, 137–146;

Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2102975118. doi: 10.1073/pnas.2102975118.PMID: 34620711.

Targeting Rac1 for the prevention of atherosclerosis among U.S. Veterans with inflammatory bowel disease. Small GTPases. 2021 Jul 28:1-6. doi: 10.1080/21541248.2021.1954863. PMID: 34320903.

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2022751118. doi: 10.1073/pnas.2022751118.PMID: 33526699.

Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development. Nat Commun. 2020 Sep 23;11(1):4737. doi: 10.1038/s41467-020-18528-z.


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