Physical Activity and Weight Loss to Improve Function and Pain After Total Knee Replacement
(PI: Christine Pellegrini, Ph.D.; Co-I's: Brian Burnikel, MD., Brian Chen, JD, Ph.D.,
Daniel Del Gaizo, MD., Elizabeth Regan, Ph.D., Gabriell Turner-McGrievy, Ph.D., Frank
Voss, MD., Philip Wessinger, Sara Wilcox, Ph.D.)
The purpose of the current project is to evaluate the effectiveness of the PACE weight
loss program in adults after TKR in a fully-powered two-arm randomized controlled
Funded by the National Institute of Aging (NIA) - R01AG070004 (7/15/2021 - 6/30/2026)
An mHealth Intervention for Sedentary Behavior in Pregnant Women (PI: Abbi Lane-Cordova,
Ph.D.; Co-I's: Christine Pellegrini, Ph.D., James Cook, MD.)
The purpose of our research is to evaluate the effectiveness and perception of an
mHealth intervention aimed at reducing SB in pregnant women.
Knee Arthroplasty Activity (KARAT) Trial (PI: Elena Losina, PhD [Brigham and Women's
Hospital]; Site PI: Christine Pellegrini, PhD)
The purpose of this study is to plan a multisite clinical trial to test an innovative
application of behavioral science principles that invoke both internal motivation
(using motivational interviewing) and external motivation (using financial incentives)
to improve PA among persons with knee osteoarthritis (OA) undergoing TKR.
Funded by the National Institute of Arthritis and Musculoskeltal and Skin Diseases
(NIAMS) (9/17/2020 - 8/31/2021)
Reducing Sedentary Time using an Innovative mHealth Intervention among Total Knee
Replacement Patients (PI: Christine Pellegrini, Ph.D.; Co-I's: Sara Wilcox, Ph.D.,
Julia Lee, Ph.D.)
The purpose of this study is to examine the innovative approach of decreasing sedentary time prior to targeting physical activity
in adults after TKR and determine if a remotely-delivered, mHealth sedentary reduction
intervention can decrease sedentary time.
Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (4/1/2020 - 1/23/2023)
Phone Coaching as a Rescue Strategy for Early Non-Responders Enrolled in an Internet-Delivered
Weight Loss Program (PI: Jessica Unick, PhD [The Miriam Hospital]; Co-I: Christine
The aim of this study is to compare weight outcomes among early non-responders randomized
to Brief phone coaching, Extended phone coaching, and Control over the course of an
internet-delivered weight loss intervention in overweight and obese adults.
Funded by NIH/NIDDK – R01 DK117843 (9/18/2018 - 6/30/2023)
Challenge the conventional. Create the exceptional. No Limits.