• Evaluating Alternative Delivery Models for Arthritis Self-Management Interventions (PI: Christine Pellegrini, PhD.; Co-I: Sara Wilcox, PhD.)
  • This study aims to evaluate a phone-based version of the Walk with Ease program in adults with arthritis in a randomized controlled trial. Outcomes to be examined include pain, function, physical activity, depressive symptoms, self-efficacy, work loss, and healthcare utilization.
  • Funded by The Centers for Disease Control and Prevention - U48DP006401 (9/30/2021-9/29/2024)
• Physical Activity and Weight Loss to Improve Function and Pain After Total Knee Replacement (PI: Christine Pellegrini, Ph.D.; Co-I's: Brian Burnikel, MD., Brian Chen, JD, Ph.D., Elizabeth Regan, Ph.D., Gabrielle Turner-McGrievy, Ph.D., Philip Wessinger, Sara Wilcox, Ph.D.)
  • The purpose of the current project is to evaluate the effectiveness of the PACE weight loss program in adults after TKR in a fully-powered two-arm randomized controlled trial.
  • Funded by the National Institute of Aging (NIA) - R01AG070004 (7/15/2021 - 6/30/2026)
• Reducing Sedentary Time using an Innovative mHealth Intervention among Total Knee Replacement Patients (PI: Christine Pellegrini, Ph.D.; Co-I's: Sara Wilcox, Ph.D., Julia Lee, Ph.D.)
  • The purpose of this study is to examine the innovative approach of decreasing sedentary time prior to targeting physical activity in adults after TKR and determine if a remotely-delivered, mHealth sedentary reduction intervention can decrease sedentary time. 
  • Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (4/1/2020 - 1/23/2023)
• Energize! Internet-Delivered Physical Activity Program for Adults with Knee Replacement (PI: Christine Pellegrini, Ph.D.; Co-I: Chih-Hsiang Yang, Ph.D.)
  • The purpose of this study is to examine the effects of an internet-based physical activity program on moderate to vigorous intensity physical activity (MVPA), pain, self-reported physical function, and cognitive function in adults with TKR at 3 months (post intervention) and 6 months (maintenance).
  • Funded by The University of South Carolina Office of Research and Health Sciences (7/1/2023 - 7/1/2024)